University of Birmingham > Talks@bham > School of Mathematics Events > Inaugural Seminar: Multiscale Mechanobiology: How forces, material properties and geometry affect biological systems

Inaugural Seminar: Multiscale Mechanobiology: How forces, material properties and geometry affect biological systems

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If you have a question about this talk, please contact Chris Parker.

Single cells are not just complex chemical machines, where networks of interacting molecules provide a mechanism for signal integration and direction of responses. Recent evidence also highlights that physical properties, including stiffness of the environment, surrounding fluid flow or forces from neighbouring cells may directly affect cell behaviour. One goal of my research is to mathematically characterise the complex interplay of mechanical and chemical regulation of cells. For instance, I will show some earlier work where we demonstrated that cell geometry can directly affect the behaviour of cells through changes in subcellular compartmentalisation of signalling molecules. This work led to a number of mathematical challenges, including the solution of reaction-diffusion equations on coupled bulk-boundary domains as well as techniques to approximate these equations.

This talk is part of the School of Mathematics Events series.

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