Modelling bacteria: how can mathematics contribute to combatting AMR?

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• Dr Jamie Wood, University of York
• Monday 20 March 2017, 15:00-16:00
• Strathcona LT7.

If you have a question about this talk, please contact David Smith.

Over the last few years my research has become increasingly focussed on bacteria, their metabolism, their genetics and their collective behaviour. This kind of research has increasing relevance, with so much concern focussed at the growing threat of anti-microrobial resistance (AMR) and the medical implications of our failure to tackle it. I will quickly review this threat and then focus on two systems which I have studied in my group recently. Firstly, the importance of plasmid dynamics in bacteria and some attempts at modelling this. I will present a lot of empirical data in this section and finish with a slightly scary empirical finding relating to AMR . Secondly I will look in more mathematical detail at a classic systems biology model of quorum sensing in Pseudomonas aeruginosa and present some new findings. I will conclude by presenting preliminary results form a simplified model of P. aeruginosa in a patient setting and try to give a sense of how we might pull mathematical results at different levels of model description to have some impact on healthcare descisions.

This talk is part of the Applied Mathematics Seminar Series series.

This talk is included in these lists:

• Applied Mathematics Seminar Series
• School of Mathematics Events
• Strathcona LT7

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