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Mathematical Models for Tissue Engineering

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Tissue engineers aim to grow artificial tissue in the laboratory to replace tissue in the body that has become damaged due to age, trauma or disease, or to use as an alternative to animal models for drug testing. When engineering tissues in vitro, a key challenge is to mimic the biochemical and biomechanical environment experienced by cells in vivo, in order to promote the engineering of fully functional tissue. The development and solution of mathematical models of these complex biological systems has a key role to play in understanding the local cell environment, and in informing the choice of operating conditions of the experimental system. In this talk, I will illustrate some approaches we have made to mathematically model in vitro tissue engineering systems, and highlight some of the modelling predictions which can be exploited in the laboratory.

This talk is part of the Applied Mathematics Seminar Series series.

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